Sinai EM Journal Club

Emergency Medicine Discussion Forum

Validation of San Fransisco Syncope Rule

This month's Annals (May 2006) has an article from Quinn et al. (QuinnAEM-5-06) purporting to validate the San Fransisco Syncope Rule. Also known as "CHESS", the "rule" is positive if any one of the following is true:

  • CHF in the past medical history
  • Hematocrit < 30
  • EKG shows nonsinus rhythm or new changes
  • Shortness of Breath
  • Systolic < 90 mmHg

In a prospective cohort series, the rule was 98% sensitive (95%CI = 89-100%), 56% specific in predicting "adverse events" within 30 days. Basically, scoring a negative on the San Fransisco rule can make you feel better about sending a patient home. Though, let's be honest, if the test is really 89% sensitive (as the confidence interval allows) than this rule creates an "unnaceptably high" rate of serious outcomes. More below! Read more »

May 26, 2006 Posted by Nick | Risk Stratification, Syncope | | 2 Comments