Lyse and Statistics: GRACIA-2 vs. ASSENT-4
The first Journal Club of the year got off to a thunderous start (there was lightning and flooding, too, and an explosion a little bit later). Those who braved the elements participated in a discussion about thrombolysis before angioplasty for STEMI, centered on two papers with two different conclusions about its benefit.
The primary paper we covered was from the GRACIA-2 non-inferiority RCT, called Primary angioplasty vs. early routine post-fibrinolysis angioplasty for acute myocardial infarction with ST-segment elevation (from the European Heart Journal 2007 Vol. 28, p949-960).
Our secondary paper was from the ASSENT-4 RCT, called Primary verses tenecteplase-facilitated percutaneous coronary intervention in patients with ST-segment elevation acute MI (from the Lancet 2006: Vol 367, p569-578). Read more »
